hochbaum lab Harvard Medical SchoolBeth Israel Deaconess Medical Center

publications

google scholar

2025

  • Thyroid hormone and the brain

    D. R. Hochbaum†, B. L. Sabatini†

    Current Biology 35, 20, 999–1004

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    Current Biology cover, volume 35 number 20: Brain–body interactions.

2024

  • Graphical abstract: thyroid hormone remodels frontal cortex to coordinate metabolism and exploration.

    Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration

    D. R. Hochbaum, L. Hulshof*, A. Urke*, W. Wang*, A. C. Dubinsky*

    Cell 187, 1–19

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  • Longevity, demographic characteristics, and socio-economic status are linked to triiodothyronine levels in the general population

    R. Lawton, B. L. Sabatini†, D. R. Hochbaum†

    Proceedings of the National Academy of Sciences 121 (2), e2308652121

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earlier
2022

  • Analysis of thermogenesis experiments with CalR

    M. D. Cortopassi, D. Ramachandran, W. B. Rubio, D. R. Hochbaum, B. L. Sabatini

    Brown Adipose Tissue: Methods and Protocols, 43–72

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2021

  • Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability

    G. L. Boulting, E. Durresi, B. Ataman, M. A. Sherman, K. Mei

    Nature Neuroscience 24, 437–448

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2020

  • Anatomical and single-cell transcriptional profiling of the murine habenular complex

    M. L. Wallace, K. W. Huang, D. R. Hochbaum, M. Hyun, G. Radeljic

    eLife 9, e51271

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2019

  • Distinct cortical-thalamic-striatal circuits through the parafascicular nucleus

    G. Mandelbaum, J. Taranda, T. M. Haynes, D. R. Hochbaum, K. W. Huang

    Neuron 102, 636–652

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  • A supervised, symmetry-driven, GUI toolkit for mouse brain stack registration and plane assignment

    M. Cicconet, D. R. Hochbaum

    bioRxiv 781880

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2018

  • Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex

    S. Hrvatin*, D. R. Hochbaum*, M. A. Nagy*, M. Cicconet, K. Robertson

    Nature Neuroscience 21, 120–129

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  • A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

    K. D. Piatkevich, E. E. Jung, C. Straub, C. Linghu, D. Park

    Nature Chemical Biology 14, 352–360

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2017

  • Early-life gene expression in neurons modulates lasting epigenetic states

    H. Stroud, S. C. Su, S. Hrvatin, A. W. Greben, W. Renthal

    Cell 171, 1151–1164

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  • Bots for software-assisted analysis of image-based transcriptomics

    M. Cicconet, D. R. Hochbaum, D. L. Richmond, B. L. Sabatini

    Proceedings of the IEEE International Conference on Computer Vision Workshops, 134–142

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2016

  • Roadmap on neurophotonics

    Y. K. Cho, G. Zheng, G. J. Augustine, D. R. Hochbaum, A. Cohen

    Journal of Optics 18, 093007

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2014

  • All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

    D. R. Hochbaum*, Y. Zhao*, S. L. Farhi, N. Klapoetke, C. A. Werley

    Nature Methods 11, 825–833

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  • Bright and fast multicoloured voltage reporters via electrochromic FRET

    P. Zou, Y. Zhao, A. Douglass, D. R. Hochbaum, D. Brinks

    Nature Communications 5, 4625

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  • Flash memory: photochemical imprinting of neuronal action potentials onto a microbial rhodopsin

    V. Venkatachalam, D. Brinks, D. Maclaurin, D. R. Hochbaum, J. Kralj

    Journal of the American Chemical Society 136, 2529–2537

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  • Measuring membrane voltage with microbial rhodopsins

    A. E. Cohen, D. R. Hochbaum

    Methods in Molecular Biology 1071, 97–108

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2012

  • Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

    J. M. Kralj*, A. Douglass*, D. R. Hochbaum*, D. Maclaurin, A. E. Cohen

    Nature Methods 9, 90–95

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2011

  • Electrical spiking in Escherichia coli probed with a fluorescent voltage-indicating protein

    J. M. Kralj, D. R. Hochbaum, A. Douglass, A. E. Cohen

    Science 333, 345–348

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  • Reducing recombination losses in planar organic photovoltaic cells using multiple step charge separation

    T. D. Heidel, D. R. Hochbaum, J. M. Sussman, V. Singh, M. E. Bahlke

    Journal of Applied Physics 109, 10

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* equal contribution  ·  † corresponding author